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nf-core/duphold @ 0.0.0-0c7146d

SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. This can be used as additional information for filtering variants; for example we will be skeptical of deletion calls that do not have lower than average coverage compared to regions with similar gc-content.

Latest version: 0.0.0-0c7146d
Total downloads: 1
Source: nf-core/modules
Authors: @nvnieuwk
Maintainers: @nvnieuwk

Summary

SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. This can be used as additional information for filtering variants; for example we will be skeptical of deletion calls that do not have lower than average coverage compared to regions with similar gc-content.

Get started

Add the following snippet to your workflow script to include this module.

include { DUPHOLD } from 'nf-core/duphold'

License

MIT License

Process
Name DUPHOLD
Input 3 channels
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

alignment_file file

file containing alignments

alignment_index file

index of alignment file

sv_variants file

A variants file containing structural variants

*.{vcf,bcf}(.gz)?
snp_variants file

A variants file containing SNPs

*.{vcf,bcf}(.gz)?
snp_variants_index file

index of snp variants file

fasta file

fasta file

*.{fa,fasta,fna}
fasta_fai file

Index of fasta file

*.fai
Output 2 channels
#1 vcf tuple
meta map

Groovy Map containing sample information e.g. [ id:'test', single_end:false ]

*.vcf.gz file

The output VCF

*.vcf.gz
#2 versions_duphold tuple
${task.process} string

The name of the process

duphold string

The name of the tool

duphold -h | sed -e "s/^version: //;q" eval

The expression to obtain the version of the tool

Tool Description Homepage
duphold SV callers like lumpy look at split-reads and pair distances to find structural variants. This tool is a fast way to add depth information to those calls. https://github.com/brentp/duphold
Version 0.0.0-0c7146d
Commit ID 135d883a43b1a2324b4112cd270cf22e20835533
Release Date 08 Apr 2026 18:36:33 (UTC)
Download URL https://registry-stage.nextflow.io/api/v1/modules/nf-core%2Fduphold/0.0.0-0c7146d/download
OCI Store URL https://public.cr.stage-seqera.io/v2/nextflow/plugin-stage/modules/nf-core/duphold/blobs/sha256:63fa14fca2c0ad40cb7c3ee9716505902f377e4b77a3984919db279f4f27784d
Size 2.9 KB
Checksum sha256:63fa14fca2c0ad40cb7c3ee9716505902f377e4b77a3984919db279f4f27784d
Downloads 1
Version Date Status Downloads Size Diff
0.0.0-0c7146d 08 Apr 2026 18:36:33 (UTC) 1 2.9 KB -