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nf-core/bigslice @ 0.0.0-1d8acb2

A scalable tool for large-scale analysis of Biosynthetic Gene Clusters (BGCs). It takes genome regions in GenBank format along with an HMM database and produces a SQLite database and FASTA outputs of predicted features.

Latest version: 0.0.0-1d8acb2
Total downloads: 1
Source: nf-core/modules
Maintainers: @vagkaratzas @SkyLex

Summary

A scalable tool for large-scale analysis of Biosynthetic Gene Clusters (BGCs). It takes genome regions in GenBank format along with an HMM database and produces a SQLite database and FASTA outputs of predicted features.

Get started

Add the following snippet to your workflow script to include this module.

include { BIGSLICE } from 'nf-core/bigslice'

License

MIT License

Process
Name BIGSLICE
Input 3 channels
#1 tuple
meta map

Groovy Map containing sample information e.g. [ id:'sample1' ]

bgc file

List of GenBank (.gbk) files containing genomic region annotations for BiG-SLiCE input. Each file represents a BGC region. The module internally organises them into the required BiG-SLiCE input folder structure (datasets.tsv and taxonomy TSV).

*.gbk
hmmdb directory

Path to the BiG-SLiCE HMM database folder containing biosynthetic and sub Pfams for annotation, in the required BiG-SLiCE format. An example directory in compressed archive format can be found here: https://github.com/medema-group/bigslice/releases/download/v2.0.0rc/bigslice-models.2022-11-30.tar.gz

export_tsv boolean

If true, runs a second BiG-SLiCE invocation to export all results from the SQLite database to TSV files under tsv_export/. Additional arguments for this step can be passed via task.ext.args2.

Output 3 channels
#1 tsv tuple
meta map

Groovy Map containing sample/dataset information

${prefix}/result/tsv_export directory

Directory containing TSV exports of all parsed BGC metadata, vectorized features and clustering results. Only present when export_tsv input is set to true.

tsv_export
#2 output tuple
meta map

Groovy Map containing sample/dataset information

${prefix}/result directory

BiG-SLiCE result directory containing the SQLite database (data.db), predicted feature FASTA files (tmp/**/*.fa), and optionally TSV exports (tsv_export/) when export_tsv is true.

result
#3 versions_bigslice tuple
${task.process} string

The name of the process

bigslice string

The name of the tool

2.0.2 string

The version of the tool

Tool Description Homepage
bigslice A highly scalable, user-interactive tool for the large scale analysis of Biosynthetic Gene Clusters data https://github.com/medema-group/bigslice
Version 0.0.0-1d8acb2
Commit ID 135d883a43b1a2324b4112cd270cf22e20835533
Release Date 08 Apr 2026 10:25:35 (UTC)
Download URL https://registry-stage.nextflow.io/api/v1/modules/nf-core%2Fbigslice/0.0.0-1d8acb2/download
OCI Store URL https://public.cr.stage-seqera.io/v2/nextflow/plugin-stage/modules/nf-core/bigslice/blobs/sha256:ba20504904c30da4f2406218051441227423d027f627927a5641d1d309bab570
Size 3.9 KB
Checksum sha256:ba20504904c30da4f2406218051441227423d027f627927a5641d1d309bab570
Downloads 1
Version Date Status Downloads Size Diff
0.0.0-1d8acb2 08 Apr 2026 10:25:35 (UTC) 1 3.9 KB -